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    Patricia Mendoza Garcia

    Patricia Mendoza Garcia

    Postdoctoral Researcher

    Education
    • PhD Molecular Biology, 2019

      Umeå University

    Latest

    • The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila central nervous system
    • Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival
    • Sustained Response to Entrectinib in an Infant With a Germline ALKAL2 Variant and Refractory Metastatic Neuroblastoma
    • DamID transcriptional profiling identifies the Snail/Scratch transcription factor Kahuli as an Alk target in the Drosophila visceral mesoderm
    • ALK ligand ALKAL2 potentiates MYCN-driven neuroblastoma in the absence of ALK mutation
    • Identification of the Wallenda JNKKK as an Alk suppressor reveal increased competitiveness of Alk-expressing cells
    • Targeting anaplastic lymphoma kinase in neuroblastoma
    • ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells
    • The Zic family homologue Odd-paired regulates Alk expression in Drosophila
    • FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase

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