Latest
- Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival
- Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
- Identification of the Wallenda JNKKK as an Alk suppressor reveal increased competitiveness of Alk-expressing cells
- ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells
- The scaffolding protein Cnk binds to the receptor tyrosine kinase Alk to promote visceral founder cell specification in Drosophila
- The Zic family homologue Odd-paired regulates Alk expression in Drosophila
- Brigatinib, an anaplastic lymphoma kinase inhibitor, abrogates activity and growth in ALK-positive neuroblastoma cells, Drosophila and mice
- FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase